Training Videos & Webinars

OECD test guideline training videos

• OECD Test Guideline 492: Reconstructed human Cornea-like Epithelium (RhCE) test method for identifying chemicals not requiring classification and labelling for eye irritation or serious eye damage (EpiOcular).
  Click HERE for video.
• OECD Test Guideline 439: In Vitro Skin Irritation—Reconstructed Human Epidermis Test Method.
  Click HERE for video.
• OECD Test Guideline 437: Bovine Corneal Opacity and Permeability Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage.
  Click HERE for video.
• OECD Test Guideline 435: In Vitro Membrane Barrier Test Method for Skin Corrosion (Corrositex).
  Click HERE for video.

Webinars hosted by the Institute for In Vitro Sciences can be found here.

• The 3T3 Neutral Red Uptake Phototoxicity Test (2016)
• Regulatory Initiatives for New Approaches to Traditional Toxicity Testing (2016)
• In Vitro 3T3 Phototoxicity Assay Practical Experiences: Assay Optimization and Challenges (2015)
• Skin Irritation and Corrosion (2014)
• KeratinoSens Assay for Identifying Skin Sensitizers (2014)
• Reconstructed Human Skin Micronucleus Assay (RSMN): A Novel Micronucleus Assay in a 3D Human Skin Model (2014)
• Integrated Testing Strategies for In Vitro Skin Sensitization Testing (2013)
• In Vitro Phototoxicity Assays (2013)
• Serious Eye Damage and Eye Irritation (2013)
• Short Time Exposure (STE) Assay: Method and Use (2013)
• Revisiting Skin Irritation Testing Strategies Applying Non-Animal Test Methods (2012)
• Current Perspectives and New Directions Using the BCOP Assay—Applications in the Regulatory Arena (2011)

Webinar series on REACH testing co-hosted by the PETA International Science Consortium can be found here.

• OECD QSAR Toolbox and Read-across (2014)
• Skin Irritation and Corrosion (2014)
• Serious Eye Damage and Eye Irritation (2014)
• Skin Sensitization (2015)
• Alternative Approaches to Mammalian Acute Systemic Toxicity Testing (2015)
• (Zebra)Fish Embryo Acute Toxicity Test to Predict Short Term Toxicity to Fish (and Beyond) (2015)
• The Regulatory Processes Involved in Acceptance of Non-Animal Tests (2015)

Webinar series on alternative approaches for acute inhalation toxicity co-hosted by the PETA International Science Consortium can be found here.

• Current testing practices: regulatory requirements and non-regulatory testing (2016)
• State-of-the-science, practical application, and dosimetry considerations for in vitro and ex vivo methods (2016)
• State-of-the-science and practical application of in silico methods (2016)
• GHS additivity approach to classify mixtures based on ingredient toxicity (2016)
• Adverse outcome pathways (2016)
• 21^st century testing approaches

3D Tissue Models

• Organotypic In VitroHuman Respiratory Models of the Tracheobronchial and Alveolar Epithelium—EpiAirway^TM and EpiAlveolar^TM (hosted by MatTek; 2014)
  Click HERE for video.
• Organovo: Use of Bioprinted 3D Human Tissues for the Assessment of Drug Toxicity
  Click HERE for webinar.

Adverse Outcome Pathways

• Adverse Outcome Pathway (AOP) Learning Channel
  Click HERE for multiple AOP-related videos.
• Human Toxicology Project Consortium AOP Online Course
  Click HERE for course modules.
• Adverse Outcome Pathways: From Research to Regulation (three-day workshop co-sponsored by the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) and the Physicians Committee for Responsible Medicine; 2014)
  Click HERE for video.
• Introduction to Effectopedia (2014)
  Click HERE for video.

Exposure & Dosimetry

• An overview of EPA’s Endocrine Disruption Screening Program’s plans for using biological activity data identified through high-throughput screening combined with high-throughput exposure estimates to prioritize chemicals for estrogen-related activity (part of the Computational Toxicology Communities of Practice monthly webinar series; 2015)
  Click HERE for video.
• ICCVAM Communities of Practice Webinar: Reverse Toxicokinetics: Using In VitroData to Estimate Exposures that Could Be Associated with Adverse Effects In Vivo (2015)
  Click HERE for video.
• Incorporating Population Variability and Sensitive Subpopulations into Dosimetry for High-Throughput Toxicity Testing (part of the Computational Toxicology Communities of Practice monthly webinar series; 2013)
  Click HERE for video.

Genotoxicity

• Society of Toxicology Medical Device and Combination Product Specialty Section webinar Evaluation of Medical Devices for Genetic Toxicity: A Global Perspective
  Click HERE for webinar.
• Cyprotex In Vitro Strategies for Regulatory Genotoxicity Testing
  Click HERE for video.

In Silico Modeling and Read-Across

• OECD QSAR Toolbox training resources
  Click HERE for presentations.
• OECD and European Chemicals Agency webinar on QSAR Toolbox version 4.0 with new features
  Click HERE for webinar.
• European Chemicals Agency OECD QSAR Toolbox training
  Click HERE for video.
• Simulations Plus webinars on their modeling and simulation software
  Click HERE for videos.
• Cheminformatics and Toxicogenomics for Toxicology Prediction and Mechanistic Insight (part of the Computational Toxicology Communities of Practice monthly webinar series; 2013)
  Click HERE for video.
• TOXLINE tour of database containing references covering the biochemical, pharmacological, physiological, and toxicological effects of drugs and other chemicals
  Click HERE for tutorial.
• ChemIDplus tour of database containing more than 400,000 chemical records with information about names, structures, chemical properties, and toxicity
  Click HERE for part 1 tutorial, and HERE for part 2 tutorial.
  A video on drawing a chemical structure in ChemIDplus can be viewed HERE.
• Lhasa Limited Summation of Toxicity Data in Vitic
  Click HERE for webinar.
• ToxBank Tutorials
  Click HERE for tutorials.

Integrated Approaches to Testing and Assessment

• Society of Toxicology In Vitro and Alternative Methods Specialty Section webinar Use of Integrated Approaches to Testing and Assessment (IATA) To Facilitate Regulatory Use of Non-Standard Testing Methods
  Click HERE for webinar.

Medical Training

• SynDaver Labs synthetic tissue models of the human body
  Click HERE for video.

Organs-on-Chips

• Physiologically-relevant tissue models using a high-throughput Organ-on-a-Chip platform
  (hosted by MIMETAS, 2017)
  Click HERE for webinar.

Pyrogenicity

• PyroGene™ Recombinant Factor C Assay—An Animal-free Alternative Method for Endotoxin Detection (hosted by Lonza; 2013)
  Click HERE for video.
• The Whole Blood Assay: Detecting a Broad Spectrum of Pyrogens and Examples for Medical Device Testing (hosted by EMD Millipore; 2015)
  Click HERE for video.

Recombinant Antibodies

• AbD Serotec®: Recombinant antibody webinars
  Click HERE for webinar.
• The Making of Recombinant Anti-idiotypic Antibodies for High Performance in Bioanalytical Assays (hosted by Bio-Rad; 2016)
  Click HERE for webinar.

Stem Cells

• Cellular Dynamics International webinars on their induced pluripotent stem cell products
  Click HERE for videos.

Alternatives Searches

• Office of Laboratory Animal Welfare Online Seminar—Meeting Requirements for Alternatives Searches (2014)
  Click HERE for video.
• TOXNET (TOXicology Data NETwork) database tour, including toxicology and animal testing alternatives databases
  Click HERE for tutorial.